Epstein's Impure Science: AIDS, Activism, and the Politics of Knowledge
digs into the debate about "what should be taken as a parameter to mark the success of [AIDS] treatment" (Mol's summation, 168)
"what makes a parameter appropriate is a complex question. Statistical issues, the immune system's behavior, patients' hopes and expectations, health care finances, the pharmaceutical industry's research style, government regulations--all of these are intertwined"
note that this book is also recommended by Gregg Gonsalves, here:
https://bsky.app/profile/gregggonsalves.bsky.social/post/3lq2wsm4mg22t